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Published in February issue of Elsevier's Maturitas
Amsterdam, February 28, 2012 - Elsevier, a world-leading provider of scientific, technical and medical information products and services, announced today the publication of an important clinical guide from the European Menopause and Andropause Society (EMAS) in the February issue of Maturitas. This clinical guide details the role of selective estrogen receptor modulators (SERMs) against postmenopausal osteoporosis as the European Medicines Agency (EMA) has approved the use of bazedoxifene and lasofoxifene.
Postmenopausal osteoporosis and resulting fractures have a major impact on morbidity and mortality and are major public health issues. Various therapies such as bisphosphonates, strontium ranelate and more recently denomsumab are available but these are not suitable for all women. Health concerns have been raised resulting from these therapies, such as oesophageal cancer, osteonecrosis of the jaw (ONJ) and subtrochanteric fractures with bisphosphonates and venous thromboembolism with strontiumranelate. Use of bazedoxifene and lasofoxifene will increase the number of therapeutic options available as these new SERMs point to a greater anti-fracture potential.
The decision of which type of treatment to use for osteoporosis and when to begin should be based on the need to reduce fracture risk. All treatments including SERMs should include recommendations for a healthy life style and adequate calcium and vitamin D intake. Additional benefits of different agents (i.e. climacteric symptom improvement with estrogens, breast cancer prevention for SERMS) must be considered when selecting the anti-osteoporosis drug. Furthermore what agent is used (estrogen, SERM, bisphosphonates) may vary over a woman's life time. The clinical guide from the European Menopause and Andropause Society (EMAS) details all important and necessary aspects of consideration.
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The guide is "Selective estrogen receptor modulators for postmenopausal osteoporosis" Santiago Palacios, Mark Brincat, C. Tamer Erel, Marco Gambacciani, Irene Lambrinoudaki, Mette H. Moen, Karin Schenck-Gustafsson, Florence Tremollieres, Svetlana Vujovic,
Margaret Rees, Serge Rozenberg (doi:10.1016/j.maturitas.2011.11.010). The article appears in Maturitas Volume 71, Issue 2 (February 2012) published by Elsevier.
About European Menopause and Andropause Society (EMAS)
The European Menopause and Andropause Society (EMAS) is an international society that promotes the study and dissemination of research into all aspects of midlife health and beyond in both men and women. Through its activities, EMAS aims to guarantee and provide the same standard of education and information throughout Europe on postreproductive health in both genders. The statutes of EMAS have been submitted to and accepted by the Swiss Authorities and the Society is now acknowledged by the Swiss Government and the International Menopause Society as the official Regional European Menopause Society. EMAS also belongs to the Council of affiliated Menopause Societies (CAMS) of the International Menopause Society (IMS). For more information go to: http://www.emas-online.org/Pages/home.aspx
About Maturitas
Maturitas is an international multidisciplinary peer reviewed scientific journal of midlife health and beyond, publishing original research, reviews, consensus statements and guidelines. The scope encompasses all aspects of postreproductive health in both genders ranging from basic science to health and social care.
About Elsevier
Elsevier is a world-leading publisher of scientific, technical and medical information products and services. The company works in partnership with the global science and health communities to publish more than 2,000 journals, including The Lancet and Cell, and close to 20,000 book titles, including major reference works from Mosby and Saunders. Elsevier's online solutions include SciVerse ScienceDirect, SciVerse Scopus, Reaxys, MD Consult and Nursing Consult, which enhance the productivity of science and health professionals, and the SciVal suite and MEDai's Pinpoint Review, which help research and health care institutions deliver better outcomes more cost-effectively.
A global business headquartered in Amsterdam, Elsevier employs 7,000 people worldwide. The company is part of Reed Elsevier Group PLC, a world-leading publisher and information provider, which is jointly owned by Reed Elsevier PLC and Reed Elsevier NV. The ticker symbols are REN (Euronext Amsterdam), REL (London Stock Exchange), RUK and ENL (New York Stock Exchange).
Media contact
Greyling Peoples
Elsevier
+31 20 485 3323
g.peoples@elsevier.com
[ | E-mail | Share ]
?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Clinical guide on selective estrogen receptor modulators for postmenopausal osteoporosisPublic release date: 28-Feb-2012 [ | E-mail | Share ]
Published in February issue of Elsevier's Maturitas
Amsterdam, February 28, 2012 - Elsevier, a world-leading provider of scientific, technical and medical information products and services, announced today the publication of an important clinical guide from the European Menopause and Andropause Society (EMAS) in the February issue of Maturitas. This clinical guide details the role of selective estrogen receptor modulators (SERMs) against postmenopausal osteoporosis as the European Medicines Agency (EMA) has approved the use of bazedoxifene and lasofoxifene.
Postmenopausal osteoporosis and resulting fractures have a major impact on morbidity and mortality and are major public health issues. Various therapies such as bisphosphonates, strontium ranelate and more recently denomsumab are available but these are not suitable for all women. Health concerns have been raised resulting from these therapies, such as oesophageal cancer, osteonecrosis of the jaw (ONJ) and subtrochanteric fractures with bisphosphonates and venous thromboembolism with strontiumranelate. Use of bazedoxifene and lasofoxifene will increase the number of therapeutic options available as these new SERMs point to a greater anti-fracture potential.
The decision of which type of treatment to use for osteoporosis and when to begin should be based on the need to reduce fracture risk. All treatments including SERMs should include recommendations for a healthy life style and adequate calcium and vitamin D intake. Additional benefits of different agents (i.e. climacteric symptom improvement with estrogens, breast cancer prevention for SERMS) must be considered when selecting the anti-osteoporosis drug. Furthermore what agent is used (estrogen, SERM, bisphosphonates) may vary over a woman's life time. The clinical guide from the European Menopause and Andropause Society (EMAS) details all important and necessary aspects of consideration.
###
The guide is "Selective estrogen receptor modulators for postmenopausal osteoporosis" Santiago Palacios, Mark Brincat, C. Tamer Erel, Marco Gambacciani, Irene Lambrinoudaki, Mette H. Moen, Karin Schenck-Gustafsson, Florence Tremollieres, Svetlana Vujovic,
Margaret Rees, Serge Rozenberg (doi:10.1016/j.maturitas.2011.11.010). The article appears in Maturitas Volume 71, Issue 2 (February 2012) published by Elsevier.
About European Menopause and Andropause Society (EMAS)
The European Menopause and Andropause Society (EMAS) is an international society that promotes the study and dissemination of research into all aspects of midlife health and beyond in both men and women. Through its activities, EMAS aims to guarantee and provide the same standard of education and information throughout Europe on postreproductive health in both genders. The statutes of EMAS have been submitted to and accepted by the Swiss Authorities and the Society is now acknowledged by the Swiss Government and the International Menopause Society as the official Regional European Menopause Society. EMAS also belongs to the Council of affiliated Menopause Societies (CAMS) of the International Menopause Society (IMS). For more information go to: http://www.emas-online.org/Pages/home.aspx
About Maturitas
Maturitas is an international multidisciplinary peer reviewed scientific journal of midlife health and beyond, publishing original research, reviews, consensus statements and guidelines. The scope encompasses all aspects of postreproductive health in both genders ranging from basic science to health and social care.
About Elsevier
Elsevier is a world-leading publisher of scientific, technical and medical information products and services. The company works in partnership with the global science and health communities to publish more than 2,000 journals, including The Lancet and Cell, and close to 20,000 book titles, including major reference works from Mosby and Saunders. Elsevier's online solutions include SciVerse ScienceDirect, SciVerse Scopus, Reaxys, MD Consult and Nursing Consult, which enhance the productivity of science and health professionals, and the SciVal suite and MEDai's Pinpoint Review, which help research and health care institutions deliver better outcomes more cost-effectively.
A global business headquartered in Amsterdam, Elsevier employs 7,000 people worldwide. The company is part of Reed Elsevier Group PLC, a world-leading publisher and information provider, which is jointly owned by Reed Elsevier PLC and Reed Elsevier NV. The ticker symbols are REN (Euronext Amsterdam), REL (London Stock Exchange), RUK and ENL (New York Stock Exchange).
Media contact
Greyling Peoples
Elsevier
+31 20 485 3323
g.peoples@elsevier.com
[ | E-mail | Share ]
?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
[unable to retrieve full-text content]February 24, 2012 | Author: John A. Ballard | Posted in Health & Fitness. You can actually avoid going to the doctor and treat hemorrhoids in your home, you can use methods like witch hazel, analgesics, sitz baths, topical cream or NSAIDS.
[unable to retrieve full-text content]AP - Soaring gasoline prices are threatening to undercut President Barack Obama's re-election prospects and offering Republicans an easy target. With prices pushing $4 a gallon and threatening to go even higher, Obama sought Thursday to confront rising public anxiety and strike back at his GOP critics.
It is said that the song Wipe Out launched a generation of drummers.? In the world of information security, the classic Applied Cryptography: Protocols, Algorithms, and Source Code in C by Bruce Schenier may have been the book that launched a generation of new cryptographers.
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Schenier latest work of art is Liars and Outliers: Enabling the Trust that Society Needs to Thrive.? For those that are looking for a follow-up to Applied Cryptography, this it is not.? In fact, it is hard to classify this as an information security title and in fact the book is marked for the current affairs / sociology section.? Whatever section this book ultimately falls in, the reader will find that Schneier is one of the most original thinkers around.
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In Applied Cryptography Schneier dealt with the pristine world of mathematical cryptography where aspects of pure mathematics could be demonstrably proven.? For example, non-repudiation is absolutely provable.?
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In Liars and Outliers, Schneier moves from the pristine world of mathematics into the muddy world of human trust.? Non-repudiation is no longer an absolute in a world where a Windows kernel can be compromised and end-users can be victims of social engineering.
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The book addresses the fundamental question of how does society function when you can't trust everyone.? Schneier notes that nothing in society works without trust.? It's the foundation of communities, commerce, democracy, in truth - everything.? And Schneier deals extensively with social and moral pressures that effect trust.??????
Liars and Outliers is very similar to books Umberto Eco, that have a Renaissance feel to them; bringing myriad and diverse topics together.? Schenier does this here and intertwines topics such as game theory, evolution, surveillance, existentialism and much more.? Schneier?s brilliance is that he is able to connect seemingly disparate dots around information security and society, and show how they are in truth tightly coupled.
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In the book, Schneier makes note of those that don?t follow the rules. He calls these people defectors, and these are the liars and outliers of the book.? The book notes that everything is a trade-off, and these defectors are the ones that try to break the rules.?
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An overall theme of the book, in which Schneier touches and references sociology, psychology, economics, criminology, anthropology, game theory and much more, is that society can?t function without trust.? He writes that in our complex interconnect and global society, that we need a lot of trust.?
Schneier makes frequent reference to Dunbar?s number, which he first references in chapter 2.? Dunbar's number was first proposed by British anthropologist Robin Dunbar and is a theoretical cognitive limit to the number of people with whom one can maintain stable social relationships.? It is generally in the area of 150.? So when someone sees a person with 3,000 Facebook friends, something is clearly amiss.
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In chapter 9 on institutional pressures, Schneier takes a very broad look at threats facing society today.? One of the biggest perceived threats we have today is terrorism, and the book astutely notes that we can never ensure perfect security against terrorism.?
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If Schneier had his way, the TSA budget would be measured in the millions, not billions of dollars.? He incisively observes that all the talk of terrorism as an existential threat to society is utter nonsense.? As long as terrorism is rare enough (which it is), and most people survive (which they do), society will survive.? He writes that while that observation is true, it is not politically viable for our leaders to come out and say that.?
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While the book is heavy on the people focus, Schneier also acknowledges that sometimes and for some people, the incentives to commit crimes are worth the risk.? To deal with those, that is where security technologies come into play.
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An interesting observation made in chapter 10 around technology is that sometimes the technological changes have absolutely nothing to do with the societal dilemma being secured.? For example, he notes that between the ubiquity of keyboards and the tendency for teachers to focus on standardized tests, cursive is no longer being taught that much in schools.? The result is that signatures are more likely to be either printed text is an illegible scrawl; making them easier to forge.? Which in turns creates new security risks.
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In the book Schneier makes scores of astute observations on how society functions around security.? He notes in chapter 16 that we are currently in a period of history where technology is changing faster than it ever has.? The worry is that if technology changes too fast, the attackers will be able to innovate so much faster than society can that the imbalance become even greater; with failures that negatively affect society.?
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In many of the examples in the book, Schneier paints a dark picture given the advantage that the attackers and defectors have.? But he also notes that we are in a period of history where the ability for large-scale cooperation is greater than it has ever been before. On that topic, he refers to the book The Penguin and the Leviathan: How Cooperation Triumphs over Self-Interest by Yochai Benkler where he writes that the Internet can and has enabled cooperation on a scale never before seen.? And that politics, backed by science, is ready to embrace this new cooperation.
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On the lighter side, in chapter 17, Schneier notes that Mussolini didn?t make the trains run on time; he just made it illegal to complain about them.
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Schneier notes at the end of the book that its lesson isn?t that defectors will inevitably ruin everything for everyone.? Rather that we as a society need to manage societal pressure to ensure that they don?t.?
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Liars and Outliers is an absolutely fascinating and groundbreaking book.? In this election year where the candidates attempt to make sweeping simplistic promises to fix complex problems, Schneier simply answers that in our complex society, there are no simple answers.?
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In Applied Cryptography Bruce Schneier demonstrated he was quite the smart guy.? In Liars and Outliers, he shows he is even smarter than most of us first thought.
[unable to retrieve full-text content]AP - An assistant coach of the Creighton University women's basketball team has been arrested on suspicion of drunken driving.
[unable to retrieve full-text content]Learning more about TurboTax Deluxe 2011 can be done easily. When you choose to do so you will be educating yourself about the advantages of a power financial tool. With the stress and headache that can come with filing your tax returns, make sure that you have access to the tools you need to ensure you are able to complete it successfully and on time.
NEW YORK (AP) ? Carmelo Anthony sat out the New York Knicks' game against the New Orleans Hornets on Friday night because of a strained right groin.
Anthony missed his sixth straight game. The Knicks had said he was expected to be sidelined a week or two after he was hurt during a Feb. 6 victory over Utah.
Anthony worked out before the game but coach Mike D'Antoni said the All-Star forward felt pain Thursday and the decision had been made to give him extra time.
The Knicks' next game is at home Sunday against Dallas.
Anthony leads the Knicks with 22.3 points per game but has missed nine games with injuries.
Softball? It is just a game- as basic as a new baseball bat and also golf ball. But, because complex because the United states heart it stands for. It is a sports activity, business- or even religious beliefs. Ernie Harwell (The action for those North america, ?55)
Softball is an allegorical perform with regards to North america, a new graceful, complex and also understated perform of valor, fear, best of luck, mistakes, endurance with regards to fortune and also sober self-esteem. Saul Steinberg
Undoubtedly quite enthusiastic assertions! Ernie Harwell and also Saul Steinberg weren?t able to become more appropriate with regards to softball highlighting this heart of North america. And also softball is really a sport for those North america.
Softball is defined as, a new bat-and-ball sport played between a couple of clubs. Each staff is made up helpful resources to know of seven participants. With regards to the overall game should be to rating operates by simply reaching a new golf ball and also in contact with this basics. The particular basics are some crevices of any ninety days foot or so square, as well as softball stone.
An experienced recreation comprises of seven innings. A great inning is a flip at batting that many staff becomes. Anytime this fielding staff seems to obtain several outs, this clubs transition between fielding and also batting. The particular successful staff will be the staff along with nice text for better knowledge by far the most operates at the end of a sport. The softball recreation consists of no less than one umpire whom tends to make conclusions in regards to the upshot of every perform. The particular umpire typically holds guiding this catcher making sure that he has a good take a look at this hit zoom.
Specialized Major League Baseball clubs with The usa are split into the National Category (NL) and the United states Category (Alabama). Equally leagues currently have several sections every; Far east, Western side and also Main. The particular 2009-2010 nfl season, that culminate with informative sources for better knowledge the earth Line, figure out this success of Major League Baseball, annually.
A lot of people imagine that softball came from this States. Nevertheless, is a myth. Softball actually came from Great britain before 1755. This became noted from the recently-authenticated work schedule of any law firm named Bill Bray. Yet it is in the United States which softball obtained actual acceptance, although recreation does have followers in certain different places at the same time. That continues to take pleasure in exceptional acceptance in the us, to this day. It had been from the 1860s which semi-professional softball started in the united states. And it wasn?t long before newspapers started filing softball the national bet on North america.
Softball might have originated somewhere else, yet it is in the states that the correct heart of softball is celebrated. The particular music get us out to this ballgame, the unofficial softball anthem; displays this heart. Softball has surely were capture an area from the minds of most Us residents.
Tags: golf ball, loans, The unit, united states
This entry was posted on Tuesday, February 14th, 2012 and is filed under Health & Fitness. You can follow any responses to this entry through RSS 2.0. Both comments and pings are currently closed.
An outline concerning international criminal law and Phoenix criminal attorneys is offered in this post. When you read forward, it?s important to know that all written content published in this piece of writing is inaccurate, imprecise and can even be verified wrong within the courtroom. In order to achieve precise and complete data it is recommended that an individual privately converse with your own lawyer in order to correct your own issues.
Criminal Law Professional Suggestions
The connection of the state and its members is being managed by criminal laws. A criminal offense for that reason is actually a breach of the rules and regulations designed by the sovereign authority. The set of policies developed by the house of congress provides the purpose of leading the activities of the folks within its territory. This is the kind of law that?s stringently being imposed in all of the countries.
The sophisticated skill of a Phoenix criminal lawyer encompasses the innocence of the defendant. The supposition regarding innocence will be the most important intent of criminal Defense attorneys. The direct result of a criminal matter is really reliant on the level of expertise of the criminal Criminal law firm. Criminal legal representatives are the type of legal representatives that will be commonly classed as ?immoral? merely because have a duty to shield the legal rights of the assumed lawbreaker.
Criminal Attorney Professional Suggestions
An individual has the right to telephone a criminal law attorneys whatever function we are taking part in in the courtroom of law, and it?s as simple as looking within an online Alabama criminal law attorney. Never tell all the details to the police directly. The criminal Defense lawyers and the prosecutor lawyers are the two opposing attorneys that we all see in the court of law. Without exception choose the attorney who specializes in your predicament because they will function as a large aspect in determining if justice that?s being done or not.
Dont be ignorant about your rights. Being the suspect does not mean being manipulated by others. Innocence of every suspect is always presumed not unless hearing under the court of law has occurred. Consulting the expertise of a Defense lawyer is a clever thing for everyone.
Attorneys who have chosen the path of a being a Texas criminal law attorney must be able to remove all or least minimize to the fullest extent the criminal charges. They meet and address questions to anyone that may be related to your case including the police and other witnesses. They persuade witnesses and other persons to witness on behalf of the suspects side. Negating illegally obtained witnesses so as other evidences are some of the duties being done by criminal Defense lawyers. Preparing the suspect in the court of law is one of the numerous objectives of a Defense lawyer.
Criminal Law Attorneys located in Your State
An instance of a violation of international code is when a person does tremendous harm to other countries just like what Adolf Hitler, Osama bin Laden and other international criminals. All forms of terrorism that may enlarge to a war is the main objective to be prevented by international law codes. The various special agreements being done in intercontinental law would be the safety of overseas staff coming from one nation to the next and also the prevention of various other offenses associated with intercontinental law.
BOSTON (Reuters) ? For the second time in less than a year, the Securities and Exchange Commission has pressed bailed-out insurer American International Group to provide more disclosures in its quarterly reports, this time on guaranteed interest rates in its life insurance business.
AIG on Monday filed copies of letters it exchanged with the SEC in December and January, all relating to its quarterly report for the third quarter of 2011.
On December 9, the SEC asked AIG to propose language, to be included in future filings, giving more precise descriptions of the guaranteed rates in its annuity and universal life accounts.
The SEC, as it sometimes does in such cases, also asked AIG for a written declaration acknowledging its responsibility to make adequate and accurate disclosures.
AIG responded December 22, proposing a table to include in future filings that would show the range of rate guarantees in each business, and how they related to the total account values for each product. It also provided the SEC with the disclosure declaration that had been requested.
The head of the SEC's accounting branch in turn emailed Chief Executive Bob Benmosche on January 10 to say the review had been completed.
Last August, AIG disclosed a series of letters between it and the SEC relating to its first-quarter report of spring 2011, in which the SEC asked for more disclosure about how and why the company assigns credit ratings to investments in its portfolio.
Such SEC requests to public companies are not unusual, though they offer some insight into what regulators look at when they review quarterly filings. Among others, Berkshire Hathaway has also received a number of such requests for more disclosure in the recent past.
AIG shares rose 42 cents to $27.08 in premarket trading from a $26.66 close on Friday.
(Reporting By Ben Berkowitz, editing by Dave Zimmerman)
If you?re bored silly of writing long text entries and endless statistics for your real estate blog or website, ?inject some creativity to your marketing and create an Infographic.
Infographics are simple, graphic representations of information or data, used to present complex info quickly and clearly.
Take a look at this real estate infographic sample on Home Affordability from CreditScore.
Here?s why we like infographic as a marketing technique:?
1. Simplicity and appeal.
Unless your prospects have the time of day, ?they probably won?t read the long text content on your site?s Buyer/Seller resource page.
Infographics segregate data into bite-sized chunks, accompanied by colorful graphics such as charts, diagrams, and illustrations.
This allows you to understand and retain the statistics presented, making your prospects more informed, whether they are looking to buy or sell a property.
2. Accessible online and offline
Since it?s published as an image, it can be easily saved on a laptop or mobile device even for offline use and can also be printed and distributed manually.
3. Viral
Infographics contribute a lot in terms of company branding and promotion?and they look so appealing that thay are instantly shareable.
A link to your website at the end of the infographic makes sure that people find their way back to your website.
4. Budget-friendly
When effectively distributed, Infographics have the potential to reach your market not unlike a paid ad but with less cost. With the right design and content, you can come up with a great Infographic that can be disseminated through various platforms.?Visual.ly is now looking into developing a platform where marketers can automatically have an infographic created and showcased.
Visual information is powerful, but requires a bit of work to create. You can ask a graphic designer to help you make sure that you?re effectively getting your message across.
Follow us on Twitter and Facebook for more real estate marketing tips!
Living in the US puts Hispanic women at high risk for preterm birthPublic release date: 11-Feb-2012 [ | E-mail | Share ]
Contact: Olivia Goodman olivia.goodman@gabbe.com 212-220-4444 University of Texas Medical Branch at Galveston
Length of residence increases risk
GALVESTON, February 7, 2012 The longer a Hispanic woman lives in the United States, the higher her risk of preterm birth (PTB), with nearly half of PTBs among Hispanic women occurring in those who were born in the U.S.
This is the main finding of a study by researchers at the University of Texas Medical Branch (UTMB) at Galveston who sought to shed light on possible environmental factors in PTB. It is one of several studies from UTMB presented this week at the Society for Maternal-Fetal Medicine's (SMFM) 32nd Annual Meeting in Dallas.
"Though we don't know whether preterm birth is predominately related to genetic or environmental factors, our research shows that preterm birth is at least strongly related to our environment in ways that are potentially preventable," said principal investigator Dr. Radek Bukowski, professor of obstetrics and gynecology in the Division of Maternal-Fetal Medicine at UTMB.
More than half a million babies are born prematurely each year in the U.S.; the cause is unknown in as many as 40 percent of cases.
Using data from a population study of more than 2,140 Hispanic women with a prior live birth who participated in the National Health and Nutrition Examination Survey (1999-2006), the researchers observed that the PTB prevalence rate for women residing in the U.S. for fewer than 10 years was four percent; after 10 years, that rate rose to 7.4 percent. Hispanic women born in the U.S. had a PTB prevalence rate of 9.5 percent.
The researchers adjusted for age, body mass index, education, marital status, income, current and prior smoking, diabetes and hypertension, among other potential factors.
"We were surprised to find that the risk was nearly twice as high for women living in the U.S. for more than 10 years and was almost three times higher for women born here," said Bukowski. "These findings confirm the link between preterm birth and environmental factors. However, it remains unclear what specific environmental features may predispose or protect women from preterm birth. That said, because the risk factors appear to have been acquired while living in the U.S., it is likely that they are modifiable," added Bukowski.
Embargoed until Thursday, February 9 at 4:15 ET.
More UTMB Research at SMFM
Additional UTMB research presented at the SMFM meeting includes:
Immune and biochemical pathways of preterm labor vary in response to specific bacteria associated with amniotic fluid infection and differ between races. Led by Dr. Ramkumar Menon, assistant professor, Division of Maternal-Fetal Medicine, researchers tested normal-term fetal membranes exposed to a range of pathogens linked to spontaneous PTB for differences in immune response and between African American and Caucasian women. They found that pathogens associated with PTB have different cytokine signatures and that those with lipopolysaccharides (LPS; lipids containing endotoxins) provide maximum immune response. Further, pathogens such as E. coli may play a role in racial disparities associated with infection-mediated PTB. Menon notes that the findings reiterate that the pathways of PTB associated with bacterial infection are not universal and that interventions should take into account the type of infection and the patient's race/ethnicity.
Embargoed until Friday, February 10 at 3:00 pm ET.
Babies born to obese mothers are at risk for metabolic syndrome as adults. Dr. Arshag Kalanderian, also from the Division of Maternal-Fetal Medicine, and his team explored whether they could activate a known biological pathway with a diabetic drug to improve the metabolic status of mouse offspring exposed to maternal obesity. They found that short-term therapy with the drug pioglitazone (PL) significantly reduced the offsprings' body weight and other metabolic changes associated with developmental programming. According to Kalanderian, this research is novel and points to a potential new role for PL and similar drugs.
Embargoed until Saturday, February 11 at 9:00 am ET.
Other UTMB researchers presented data on late-preterm birth and optimal timing of repeat cesarean sections; the novel use of statins to prevent preeclampsia and PTB; and the effects of nicotine exposure on long-term cardiovascular health of babies, among others.
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Researchers are available for interviews. Please contact olivia.goodman@gabbe.com, 212-220-4444.
ABOUT UTMB Health: Established in 1891, Texas' first academic health center comprises four health sciences schools, three institutes for advanced study, a research enterprise that includes one of only two national laboratories dedicated to the safe study of infectious threats to human health, and a health system offering a full range of primary and specialized medical services throughout Galveston County and the Texas Gulf Coast region. UTMB Health is a component of the University of Texas System and a member of the Texas Medical Center.
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?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Living in the US puts Hispanic women at high risk for preterm birthPublic release date: 11-Feb-2012 [ | E-mail | Share ]
Contact: Olivia Goodman olivia.goodman@gabbe.com 212-220-4444 University of Texas Medical Branch at Galveston
Length of residence increases risk
GALVESTON, February 7, 2012 The longer a Hispanic woman lives in the United States, the higher her risk of preterm birth (PTB), with nearly half of PTBs among Hispanic women occurring in those who were born in the U.S.
This is the main finding of a study by researchers at the University of Texas Medical Branch (UTMB) at Galveston who sought to shed light on possible environmental factors in PTB. It is one of several studies from UTMB presented this week at the Society for Maternal-Fetal Medicine's (SMFM) 32nd Annual Meeting in Dallas.
"Though we don't know whether preterm birth is predominately related to genetic or environmental factors, our research shows that preterm birth is at least strongly related to our environment in ways that are potentially preventable," said principal investigator Dr. Radek Bukowski, professor of obstetrics and gynecology in the Division of Maternal-Fetal Medicine at UTMB.
More than half a million babies are born prematurely each year in the U.S.; the cause is unknown in as many as 40 percent of cases.
Using data from a population study of more than 2,140 Hispanic women with a prior live birth who participated in the National Health and Nutrition Examination Survey (1999-2006), the researchers observed that the PTB prevalence rate for women residing in the U.S. for fewer than 10 years was four percent; after 10 years, that rate rose to 7.4 percent. Hispanic women born in the U.S. had a PTB prevalence rate of 9.5 percent.
The researchers adjusted for age, body mass index, education, marital status, income, current and prior smoking, diabetes and hypertension, among other potential factors.
"We were surprised to find that the risk was nearly twice as high for women living in the U.S. for more than 10 years and was almost three times higher for women born here," said Bukowski. "These findings confirm the link between preterm birth and environmental factors. However, it remains unclear what specific environmental features may predispose or protect women from preterm birth. That said, because the risk factors appear to have been acquired while living in the U.S., it is likely that they are modifiable," added Bukowski.
Embargoed until Thursday, February 9 at 4:15 ET.
More UTMB Research at SMFM
Additional UTMB research presented at the SMFM meeting includes:
Immune and biochemical pathways of preterm labor vary in response to specific bacteria associated with amniotic fluid infection and differ between races. Led by Dr. Ramkumar Menon, assistant professor, Division of Maternal-Fetal Medicine, researchers tested normal-term fetal membranes exposed to a range of pathogens linked to spontaneous PTB for differences in immune response and between African American and Caucasian women. They found that pathogens associated with PTB have different cytokine signatures and that those with lipopolysaccharides (LPS; lipids containing endotoxins) provide maximum immune response. Further, pathogens such as E. coli may play a role in racial disparities associated with infection-mediated PTB. Menon notes that the findings reiterate that the pathways of PTB associated with bacterial infection are not universal and that interventions should take into account the type of infection and the patient's race/ethnicity.
Embargoed until Friday, February 10 at 3:00 pm ET.
Babies born to obese mothers are at risk for metabolic syndrome as adults. Dr. Arshag Kalanderian, also from the Division of Maternal-Fetal Medicine, and his team explored whether they could activate a known biological pathway with a diabetic drug to improve the metabolic status of mouse offspring exposed to maternal obesity. They found that short-term therapy with the drug pioglitazone (PL) significantly reduced the offsprings' body weight and other metabolic changes associated with developmental programming. According to Kalanderian, this research is novel and points to a potential new role for PL and similar drugs.
Embargoed until Saturday, February 11 at 9:00 am ET.
Other UTMB researchers presented data on late-preterm birth and optimal timing of repeat cesarean sections; the novel use of statins to prevent preeclampsia and PTB; and the effects of nicotine exposure on long-term cardiovascular health of babies, among others.
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Researchers are available for interviews. Please contact olivia.goodman@gabbe.com, 212-220-4444.
ABOUT UTMB Health: Established in 1891, Texas' first academic health center comprises four health sciences schools, three institutes for advanced study, a research enterprise that includes one of only two national laboratories dedicated to the safe study of infectious threats to human health, and a health system offering a full range of primary and specialized medical services throughout Galveston County and the Texas Gulf Coast region. UTMB Health is a component of the University of Texas System and a member of the Texas Medical Center.
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(Updates with request to end Kodak Theatre contract in seventh to ninth paragraphs.)
Feb. 9 (Bloomberg) ? Eastman Kodak Co., the photography pioneer that filed for bankruptcy last month, said it will phase out the unit that makes digital cameras, pocket video cameras and digital picture frames.
Kodak will seek to license its brand to other makers of the devices as it exits cameras in the first half of 2012, the Rochester, New York-based company said today in a statement. It will book a $30 million charge and estimates saving $100 million annually, while pledging to honor warranties and provide technical support.
The move reduces Kodak?s consumer offerings to printing photos and selling film and inkjet printers, as the 131-year-old imaging company shrinks into a digital-printing specialist that intends to sell more faster, flexible commercial and consumer digital printers to profit from ink sales.
Kodak filed Chapter 11 last month after years of burning through cash when digital dissolved its film business. The company that pioneered the digital-imaging technology that gutted its iconic photography business has shed 47,000 employees since 2003 and closed 13 factories that produced film, paper and chemicals, along with 130 photo laboratories. The restructuring has already cost $3.4 billion.
Patent Sale
Kodak is trying to sell more than 1,100 digital-imaging patents, and is pursuing device makers including Apple Inc. and Research In Motion Ltd. for patent-infringements, maintaining the companies owe it royalty payments.
Bankruptcy makes it easier for Kodak to sell assets to pay for layoffs, U.K. and U.S. employee pensions and health-care benefits, and provide capital needed to install a big enough base of digital printers to eventually be profitable.
Kodak also has asked the bankruptcy court in Manhattan for permission to end its naming rights sponsorship of the Kodak Theatre in Los Angeles, which hosts the annual Academy Awards, citing significant savings from the termination.
CIM/H&H Media LP, the company that assumed the contract, said in a court filing yesterday that the name recognition of the Kodak Theatre ?is the precise benefit Kodak sought in entering into the 20-year sponsorship agreement.? Backing out of the agreement is ?not only legally impermissible, but practically impossible,? CIM/H&H Media said.
Kodak is obligated to pay $72 million over 20 years, CIM/H&H Media said.
The case is In re Eastman Kodak Co., 12-10202, U.S. Bankruptcy Court, Southern District of New York (Manhattan)
?With assistance from Joel Rosenblatt in San Francisco and Will Daley in New York. Editors: John Pickering, Stephen Farr
To contact the reporter on this story: Beth Jinks in New York at bjinks1@bloomberg.net
To contact the editors responsible for this story: John Pickering at jpickering@bloomberg.net; Ville Heiskanen at vheiskanen@bloomberg.net
San Miguel de Allende, Guanajuato, Mexico (PRWEB) January 31, 2012
Newly opened Alma Realty San Miguel offers central Mexico?s most comprehensive bilingual realty marketing services for Americans, Canadians and Mexicans looking to buy homes for sale in San Miguel de Allende, Mexico, a UNESCO World Heritage Site destination popular with retirees and second home owners.
It?s easy to get distracted while looking at homes for sale in San Miguel de Allende, Mexico, a UNESCO-designated World Heritage Site?like Florence, Italy?where people from around the world actually live, work, and play.
After all, this village sports 450 years of history etched upon its walls like the lines on a well-loved grandmother, or abuelita: cobblestone-dappled streets that demands a walker?s attention. Color-intense bougainvillea-draped walls of century-old stone. Bells chiming out the hours from 28 different churches, architectural masterpieces all.
But perhaps it?s the multitude of signs that most distract the visitor turned home-shopping dreamer: Casas en Venta en San Miguel?homes for sale in San Miguel. In this buyer?s market, Realtor signs abound on every street, sometimes several on a single home, where no American-style Multi-Listing Service (MLS) exists and exclusive listings are rare.
?I got confused just looking at the homes for sale in San Miguel,? said Daniel Arrowood, a recent visitor from Colorado who owns international properties elsewhere. ?Some homes had as many as four different realty signs on the wall. How do I know which realty agency I can trust??
For the serious home-buyer in San Miguel?whether from Canada or Mexico City?the choices can seem daunting. The village of 85,000 city-residents boasts over 60 realty agencies in most directories, yet many offer little more than a telephone number and a dated web site of musty listings.
Alma Realty San Miguel, the region?s newest real estate agency, aims to bring real estate marketing in San Miguel into the 21st century, making it easier for home buyers to find a dream home in Mexico. Top among their offerings for showing real estate listings in San Miguel is a Quick Response (QR) campaign, common elsewhere in North America, but new to Mexico.
?Without an MLS system here, potential buyers have a hard time researching homes in Mexico,? says Alma Realty San Miguel Partner Gregory R. Gunter. ?Our QR campaign provides Alma Realty?s home sellers an advantage by offering serious buyers a tour of the home on a Sunday afternoon?or after hours?when the buyer wants to know about a home immediately.?
As more international visitors travel with their smartphones?including the growing middle class from Mexico City seeking a respite from their big-city life?QR code campaigns ease the process of researching homes for sale in San Miguel while visitors with limited vacation time rush to see alternative listings.
Alma Realty San Miguel also boasts their ?Marquee Listings? provide better marketing exposure for home sellers in San Miguel than any other realty agency. ?While other agencies simply post listings to their web site,? says Gunter, ?we integrate social media in our marketing campaigns, including blogs, Tweets, YouTube posts and international press releases. No other realty agency in central Mexico matches such service.?
And although 21st century marketing sets Alma Realty San Miguel apart from their competitors, it is the firm?s local experience that counts most to neophytes unsure of whom to trust with what will likely be the largest cash transaction of their lives.
Rosewood San Miguel and the internationally-acclaimed boutique Hotel Matilda are among the commercial development sites Alma Realty Partner Ben Calderoni has brokered in his eleven years of experience in San Miguel de Allende. He has also sold homes to numerous residential clients only too happy to provide full-name testimonials?a rarity in the realty industry?on the firm?s new web site, http://www.AlmaRealtySanMiguel.com.
?Being bi-national?Mexican and American?myself,? says Calderoni, ?it?s easier to bridge the cultural gap buyers might face doing business here in San Miguel de Allende, whether from Vancouver or Mexico City. We also offer over a decade?s history of safe, secure transactions with our own U.S.-based trust or Stewart Title?s escrow services.?
Ready to join the four million new Boomers expected to make Mexico their next home over the upcoming 15 years? If so, be sure to visit Alma Realty San Miguel and learn how to best search for your new home in San Miguel de Allende.
Coronary artery disease (CAD) and prostate cancer, two seemingly unrelated conditions, may actually share similar causes, according to the findings of a drug trial.
CAD kills more adults in the US than any other cause, accounting for one in four deaths. Risk factors include inactivity, obesity, high blood pressure and cholesterol, cigarette smoking, and diabetes.
If confirmed that heart disease is tied to prostate cancer, the malignancy might be combated in part by lifestyle changes such as weight loss, exercise and a healthy diet, which are known to prevent heart disease, the journal Cancer Epidemiology, Biomarkers & Prevention reported.
"What's good for the heart may be good for the prostate," said Jean-Alfred Thomas II, post-doctoral fellow in urology at the Duke University Medical Centre, who led the study, according to a university statement.
The Duke team used data from 6,390 men enrolled in a large study called REDUCE, a four-year, randomized trial to test the prostate cancer risk reduction benefits of a drug called dutasteride.
All the participants had a prostate biopsy at the two and four-year marks. They also provided a detailed medical history that included their weight, incidence of heart disease, alcohol intake, medication use and other factors.
Having CAD increased the men's risk of prostate cancer by 35 percent, with the risk rising over time.
[unable to retrieve full-text content]There is no need to even light the BBQ grill to get the GrillKicker? smoking and this permits the user to cold smoke the food before cooking it as well as smoking the food while it is being cooked. This increased smoking time ...
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MEXICO CITY ? Mexico's conservative ruling party is gambling that this country known for machismo is ready for a female president and have chosen a devout Roman Catholic and popular former congresswoman who says she sympathizes with the causes of the poor.
Josefina Vazquez Mota, a 51-year-old economist, became the first female presidential candidate from any of Mexico's major parties late Sunday when she convincingly won the National Action Party's primary.
Her victory marks a milestone for women in Mexico, a country where they were not allowed to vote until 1953. The first female governor did not take office until 1989. Only a handful have been elected since.
National Action hopes Mexico is ready to follow in the footsteps of Brazil, Argentina, Costa Rica, Chile and other Latin American countries that have elected female leaders recently.
Vazquez Mota, who is still married to her high school sweetheart, won national attention after publishing a 1999 book titled "God, Please Make Me A Widow," which is described as a call to women to stop being afraid of developing their potential.
She has said she wrote the book based on her own experience of being a woman who chose to work over staying at home to raise her three daughters, defying the role she was expected to fulfill.
Vazquez Mota told El Universal newspaper in an interview published Monday that she has experienced Mexico's machismo first hand during her campaign.
"One of the hardest questions I have been asked is 'How will you manage the army if you are having menstrual cramps?'" she told the newspaper. "I have also been asked if I will have the courage to face criminals. My answer is that courage is not a matter of gender."
Born in Mexico City on Jan. 20, 1961, Vazquez Mota was educated at some of the country's more costly private universities and graduate schools, then worked as a financial consultant and business columnist for several years.
The fourth of seven siblings born to a paint store franchise owner and a housewife, she grew up in a middle class, traditional family. She is married to businessman Sergio Ocampo, who was her first boyfriend.
A religious woman, she asked PAN members to go to church first Sunday and then go vote for her. But she is not a typical conservative.
Vazquez Mota told Univision in an interview last year that although she didn't support abortion rights, she doesn't think the practice should be criminalized. She also told the network she believed marriage was between a man and a woman but that gay couples deserve respect.
She told El Universal that she is sympathetic with Liberation Theology, which advocates activism on behalf of the poor, and admires slain Roman Catholic Archbishop Oscar Arnulfo Romero, whose fight for the poor during El Salvador's bloody civil war made him a national hero.
Vazquez Mota formally jumped into politics when she was elected to Congress in 2000, part of a wave of political change that rolled across Mexico as Vicente Fox of her National Action Party captured the presidency and ended the 71-year hold on power of the Institutional Revolutionary Party, or PRI.
After only three months as a legislator, Vazquez Mota was pulled into Fox's Cabinet to head the Social Development Department, the first woman to hold the post.
She continued to build her political skills and reputation within her party by managing Felipe Calderon's successful 2006 presidential race, then serving as his education secretary after being elected to Congress for a second time. She supposedly had a falling out with Calderon after she was removed from Education Department.
But the affable candidate with a permanent smile faces an uphill battle against former Mexico State Gov. Enrique Pena Nieto, the PRI candidate who leads in all recent polls.
Many voters have grown disillusioned with National Action after 12 years in power, and due to growing frustration with a drug war in which more than 47,000 people have died over the past five years.
"She is offering to combat corruption, but Fox first offered that and after 12 years nothing has happened," said political analyst Jose Antonio Crespo. "Why would people believe her now?"
Besides ending corruption and improving education, she has said little about what direction she would take the country.
She won the nomination even though most analysts considered rival Ernesto Cordero, the former finance secretary, as the top choice of Calderon and the party establishment.
For Crespo, her victory was thanks to the support of PAN members displeased with Calderon's administration.
The fact that she is seen as an outsider in Calderon's camp will help her, said Andrew Selee, director of the Washington-based Mexico Institute.
"One thing that benefits her is that she has a certain amount of distance from President Calderon," Selee said. "I think she will try to project a sense of openness to new ideas ... but that may not be enough to overcome people's desire to entirely change direction."
Vazquez Mota, who was elected to the lower house of Congress for a second time in 2009 and became speaker of the house, is known as a good negotiator.
She could attract independent voters because many of them "might be reluctant on supporting the PRI because of its past authoritarian record or PRD candidate Andres Manuel Lopez Obrador (AMLO) because of his past radicalism," the U.S.-based Eurasia Group consulting firm wrote in a research note Monday.
Lopez Obrador is the candidate for the leftist Democratic Revolution Party, best remembered for narrowly losing against Calderon in 2006.
Though she has said she won't use gender as an issue during her campaign, the married mother of three, has used her family life on the campaign trail to garner the support of Mexican mothers and young voters.
"She is playing the gender card," said Soledad Loaeza, a political science professor in Colegio de Mexico who has studied the evolution of the PAN. "What I don't know is if that card will help her."
"She is a serious, hard working woman," Loaeza added. "Her main virtue was surrounding herself with experts."
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Public release date: 28-Feb-2012
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